Vitamins & minerals · INGREDIENT PROFILE
Zinc
Research topics: Immune function · Nutrient status
Also searched as: zinc, zinc gluconate, zinc acetate. Names and formulations are not necessarily interchangeable.
01 / MATCH THE FORMULA
The details to pin down.
Ingredient identity & form
Distinguish oral tablets, lozenges, and other delivery forms; document elemental zinc and the salt.
Dose, duration & study fit
Elemental dose, delivery form, duration, baseline status, and co-administered nutrients.
Record the tested dose from the original study. A study dose is not a recommended dose or proof that every claim at that dose is supported.
02 / READ IN CONTEXT
What changes the interpretation?
Separate normal immune-function claims from disease prevention or treatment endpoints, and distinguish deficient from replete populations.
- Population: Does the study population match your intended audience?
- Comparison: What changed compared with the control group—not just compared with baseline?
- Consistency: Do independent studies agree? Include null findings, limitations, and adverse events.
- Claim wording: Does the measured outcome support the strength and scope of the proposed claim?
03 / FOLLOW THE SOURCES
Research to explore.
A selected index of randomized trials and research reviews. Open the source to verify methods, results, corrections, and applicability.
2026 · Meta-Analysis · Systematic Review · review-article
Effects of Zinc Supplementation on Glycemic Control, Insulin Resistance, Inflammation and Oxidative Stress in Diabetes: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. ↗
PMID 42594341 · DOI 10.1002/edm2.70264 · PMC record available
2026 · Meta-Analysis · Systematic Review
The Role of Zinc in the Evolutionary Pattern of Pediatric Nephrotic Syndrome: A Meta-Analysis. ↗
PMID 40587383 · DOI 10.1093/nutrit/nuaf106
2026 · Randomized Controlled Trial
Effect of School-Based Physical Activity and Multi Micronutrient Supplementation on Micronutrient Concentrations Among Tanzanian Schoolchildren: Secondary Outcomes from the KaziAfya Cluster-Randomized Controlled Trial. ↗
PMID 42356367 · DOI 10.3390/nu18121980
2026 · Meta-Analysis · Systematic Review · Review
Effects of Zinc Supplementation on Anthropometric Indices and Adipokines in Adults: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. ↗
PMID 41617950 · DOI 10.1007/s12011-025-04965-8
How these references were selected
First four Europe PMC relevance-ranked MED records matching the recorded ingredient/outcome query and randomized-trial, systematic-review or meta-analysis publication types. No favorable-result filter. Bibliographic discovery only; not a full-text review or exhaustive bibliography.
Captured 2026-10-08: 4 records shown from 1,489 matching index records. Index counts describe this query, not supporting studies or evidence quality.
(TITLE_ABS:"zinc") AND (TITLE_ABS:"supplementation") AND SRC:MED AND (PUB_TYPE:"Randomized Controlled Trial" OR PUB_TYPE:"Systematic Review" OR PUB_TYPE:"Meta-Analysis")Run the recorded index search ↗04 / GO DEEPER
Guidance & source databases.
NIH ODS: Zinc↗Database links open a fresh search. Registry entries can identify ongoing or unpublished trials; registration alone is not evidence of benefit.
Educational research navigation. Not individual medical advice, a safety clearance, regulatory approval, or a complete review of this ingredient. Bibliographic snapshot: 2026-10-08.