Vitamins & minerals · INGREDIENT PROFILE
Vitamin D
Research topics: Bone health · Muscle function · Nutrient status
Also searched as: vitamin D, D3, D2, cholecalciferol, ergocalciferol. Names and formulations are not necessarily interchangeable.
01 / MATCH THE FORMULA
The details to pin down.
Ingredient identity & form
Record D2 or D3 and both micrograms and IU as reported; identify co-administered calcium or other nutrients.
Dose, duration & study fit
Baseline 25-hydroxyvitamin D, daily versus intermittent dosing, duration, age, and co-supplements.
Record the tested dose from the original study. A study dose is not a recommended dose or proof that every claim at that dose is supported.
02 / READ IN CONTEXT
What changes the interpretation?
Separate correction of deficiency from additional benefits in participants with adequate baseline status.
- Population: Does the study population match your intended audience?
- Comparison: What changed compared with the control group—not just compared with baseline?
- Consistency: Do independent studies agree? Include null findings, limitations, and adverse events.
- Claim wording: Does the measured outcome support the strength and scope of the proposed claim?
03 / FOLLOW THE SOURCES
Research to explore.
A selected index of randomized trials and research reviews. Open the source to verify methods, results, corrections, and applicability.
2026 · Meta-Analysis · Systematic Review
Vitamin D supplementation for prevention of vitamin D deficiency in preterm and low birth weight infants. ↗
PMID 42746921 · DOI 10.1002/14651858.cd011529.pub2
2026 · Meta-Analysis · Systematic Review · systematic-review
Assessing the role of vitamin D in the prevention and management of chronic rhinosinusitis: a systematic review and meta-analysis. ↗
PMID 42568492 · DOI 10.3389/fimmu.2026.1859469 · PMC record available
2026 · Systematic Review · Network Meta-Analysis
Vitamin D-containing supplementation and depressive symptom severity in adults: A Bayesian systematic review and evidence-structure assessment. ↗
PMID 42594843 · DOI 10.1016/j.clnu.2026.106751
2026 · Meta-Analysis · Systematic Review · review-article · Review
Vitamin D Status and Supplementation in Lumbar Spinal Fusion: A Systematic Review and Meta-Analysis of Radiographic and Clinical Outcomes. ↗
PMID 42675950 · PMC record available
How these references were selected
First four Europe PMC relevance-ranked MED records matching the recorded ingredient/outcome query and randomized-trial, systematic-review or meta-analysis publication types. No favorable-result filter. Bibliographic discovery only; not a full-text review or exhaustive bibliography.
Captured 2026-10-08: 4 records shown from 3,884 matching index records. Index counts describe this query, not supporting studies or evidence quality.
(TITLE_ABS:"vitamin D") AND (TITLE_ABS:"supplementation") AND SRC:MED AND (PUB_TYPE:"Randomized Controlled Trial" OR PUB_TYPE:"Systematic Review" OR PUB_TYPE:"Meta-Analysis")Run the recorded index search ↗04 / GO DEEPER
Guidance & source databases.
NIH ODS: Vitamin D↗Database links open a fresh search. Registry entries can identify ongoing or unpublished trials; registration alone is not evidence of benefit.
Educational research navigation. Not individual medical advice, a safety clearance, regulatory approval, or a complete review of this ingredient. Bibliographic snapshot: 2026-10-08.