Vitamins & minerals · INGREDIENT PROFILE
Calcium
Research topics: Bone health · Nutrient intake
Also searched as: calcium, calcium carbonate, calcium citrate. Names and formulations are not necessarily interchangeable.
01 / MATCH THE FORMULA
The details to pin down.
Ingredient identity & form
Identify the calcium compound and elemental calcium; document vitamin D and other co-ingredients.
Dose, duration & study fit
Elemental dose, dietary intake, co-supplements, age, and study duration.
Record the tested dose from the original study. A study dose is not a recommended dose or proof that every claim at that dose is supported.
02 / READ IN CONTEXT
What changes the interpretation?
Check total dietary calcium, the population, and whether the endpoint is a biomarker, bone density, or a clinical event.
- Population: Does the study population match your intended audience?
- Comparison: What changed compared with the control group—not just compared with baseline?
- Consistency: Do independent studies agree? Include null findings, limitations, and adverse events.
- Claim wording: Does the measured outcome support the strength and scope of the proposed claim?
03 / FOLLOW THE SOURCES
Research to explore.
A selected index of randomized trials and research reviews. Open the source to verify methods, results, corrections, and applicability.
2026 · Systematic Review · review-article · Network Meta-Analysis
Effectiveness of perioperative calcium and vitamin D supplementation in preventing post-thyroidectomy hypocalcaemia: network meta-analysis of randomized trials. ↗
PMID 42397982 · DOI 10.1093/bjsopen/zrag093 · PMC record available
2026 · Meta-Analysis · Systematic Review
Calcium, vitamin D, or combined supplementation to prevent fractures and falls: systematic review and meta-analysis. ↗
PMID 42161415 · DOI 10.1136/bmj-2025-088050 · PMC record available
2026 · Meta-Analysis · Systematic Review · Review
Effects of Potassium Citrate Supplementation on Bone Turnover Markers in Postmenopausal Women: A GRADE-Assessed Systematic Review, Meta-analysis and Trial Sequential Analysis. ↗
PMID 42423994 · DOI 10.1007/s00223-026-01569-9
2026 · Meta-Analysis · Systematic Review · review-article
Probiotics and Their Functional Role in Mitigating Antinutrient Effects In Vivo-A Systematic Review and Meta-Analysis. ↗
PMID 42313570 · DOI 10.1111/1541-4337.70524 · PMC record available
How these references were selected
First four Europe PMC relevance-ranked MED records matching the recorded ingredient/outcome query and randomized-trial, systematic-review or meta-analysis publication types. No favorable-result filter. Bibliographic discovery only; not a full-text review or exhaustive bibliography.
Captured 2026-10-08: 4 records shown from 2,280 matching index records. Index counts describe this query, not supporting studies or evidence quality.
(TITLE_ABS:"calcium") AND (TITLE_ABS:"supplementation") AND SRC:MED AND (PUB_TYPE:"Randomized Controlled Trial" OR PUB_TYPE:"Systematic Review" OR PUB_TYPE:"Meta-Analysis")Run the recorded index search ↗04 / GO DEEPER
Guidance & source databases.
NIH ODS: Calcium↗Database links open a fresh search. Registry entries can identify ongoing or unpublished trials; registration alone is not evidence of benefit.
Educational research navigation. Not individual medical advice, a safety clearance, regulatory approval, or a complete review of this ingredient. Bibliographic snapshot: 2026-10-08.