Vitamins & minerals · INGREDIENT PROFILE
Iron
Research topics: Nutrient status · Fatigue outcomes
Also searched as: iron, ferrous sulfate, ferrous bisglycinate. Names and formulations are not necessarily interchangeable.
01 / MATCH THE FORMULA
The details to pin down.
Ingredient identity & form
Record ferrous or ferric form and elemental iron; distinguish oral products from non-oral interventions.
Dose, duration & study fit
Elemental dose, schedule, ferritin and hemoglobin at baseline, duration, and population.
Record the tested dose from the original study. A study dose is not a recommended dose or proof that every claim at that dose is supported.
02 / READ IN CONTEXT
What changes the interpretation?
Interpret fatigue or performance outcomes alongside baseline iron status. Disease-management studies require a separate claim-context review.
- Population: Does the study population match your intended audience?
- Comparison: What changed compared with the control group—not just compared with baseline?
- Consistency: Do independent studies agree? Include null findings, limitations, and adverse events.
- Claim wording: Does the measured outcome support the strength and scope of the proposed claim?
03 / FOLLOW THE SOURCES
Research to explore.
A selected index of randomized trials and research reviews. Open the source to verify methods, results, corrections, and applicability.
2026 · Meta-Analysis · Systematic Review
Oral or parenteral iron supplementation to reduce deferral, iron deficiency and/or anaemia in blood donors. ↗
PMID 42240175 · DOI 10.1002/14651858.cd009532.pub3
2026 · Randomized Controlled Trial
Effect of iron therapy on fatigue symptoms in non-anaemic iron deficient women of reproductive age- A Randomized Controlled Trial. ↗
PMID 41736325 · DOI 10.47391/jpma.22068
2026 · Meta-Analysis · Systematic Review · review-article
The Effect of Diet and Dietary Supplements on Iron Status of Active Females: A Systematic Review and Meta-analysis of Interventional Trials. ↗
PMID 42271116 · DOI 10.1007/s40279-026-02464-x · PMC record available
2026 · Randomized Controlled Trial
Effect of calcium supplementation in pregnancy on maternal anemia and iron status: secondary analyses of two randomized trials in India and Tanzania. ↗
PMID 42067065 · DOI 10.1016/j.ajcnut.2026.101338
How these references were selected
First four Europe PMC relevance-ranked MED records matching the recorded ingredient/outcome query and randomized-trial, systematic-review or meta-analysis publication types. No favorable-result filter. Bibliographic discovery only; not a full-text review or exhaustive bibliography.
Captured 2026-10-08: 4 records shown from 3,037 matching index records. Index counts describe this query, not supporting studies or evidence quality.
(TITLE_ABS:"iron") AND (TITLE_ABS:"supplementation" OR TITLE_ABS:"fatigue" OR TITLE_ABS:"ferritin") AND SRC:MED AND (PUB_TYPE:"Randomized Controlled Trial" OR PUB_TYPE:"Systematic Review" OR PUB_TYPE:"Meta-Analysis")Run the recorded index search ↗04 / GO DEEPER
Guidance & source databases.
NIH ODS: Iron↗Database links open a fresh search. Registry entries can identify ongoing or unpublished trials; registration alone is not evidence of benefit.
Educational research navigation. Not individual medical advice, a safety clearance, regulatory approval, or a complete review of this ingredient. Bibliographic snapshot: 2026-10-08.